HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 530
+	Hs
		369692 DDB1_HUMAN (1-1140): 0: 1424: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1073088 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		487458 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1014175 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		487376 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59