Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1
Interactor 2: CRBN (Q96SW2)
Protein cereblon
Gene: CRBN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29892083, 35271311, 16964240, 26231201, 25860244, 27142104, 23983124, 26990986, 27294876, 27338790, 28425720, 24292625, 29370161, 30190590, 32132601, 32235678, 32391793, 36378961, 20223979, 25108355 and 2 others
more... |
| Identification Methods | pull down, affinity chromatography technology, x-ray crystallography, biochemical, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CPSF_A~LON_substr_bdg, CPSF_A~Yippee-Mis18, LON_substr_bdg~MMS1_N, MMS1_N~Yippee-Mis18 |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
