HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: HDAC8 (Q9BY41)
Histone deacetylase 8 (HD8) (EC 3.5.1.98) (Protein deacetylase HDAC8) (EC 3.5.1.-) (Protein decrotonylase HDAC8) (EC 3.5.1.-)
Gene: HDAC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26679995
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 377
+	Hs
		1038418 DDB1_HUMAN (1-1140): 0: 1424: 100.00		HDAC1_HUMAN (6-376): 0: 539: 39.79
+	Mm
		140263 DDB1_MOUSE (1-1140): 0: 1422: 99.65		HDAC1_MOUSE (6-376): 0: 540: 39.79
+	Hs
		1082308 DDB1_HUMAN (1-1140): 0: 1424: 100.00		HDAC2_HUMAN (11-376): 3.92e-180: 511: 40.60
+	Mm
		936386 DDB1_MOUSE (1-1140): 0: 1422: 99.65		HDAC2_MOUSE (11-376): 1.87e-179: 509: 40.60
+	Hs
		177309 DDB1_HUMAN (1-1140): 0: 1424: 100.00		HDAC3_HUMAN (12-376): 1.22e-173: 492: 40.60
+	Hs
		880742 DDB1_HUMAN (1-1140): 0: 1424: 100.00		HDAC4_HUMAN (1-366): 8.21e-128: 394: 20.76
+	Mm
		1112318 DDB1_MOUSE (1-1140): 0: 1422: 99.65		HDAC6_MOUSE (4-328): 2.83e-105: 336: 23.65
+	Sp
		140681 RIK1_SCHPO (12-1094): 0: 679: 18.91		PHD1_SCHPO (11-376): 6.03e-165: 470: 34.96
+	Hs
		1014212 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		HDAC6_HUMAN (1-328): 2.59e-94: 307: 24.78