HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: NRBP2 (Q9NSY0)
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16)
Gene: NRBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CPSF_A~Pkinase, MMS1_N~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 501
+	Hs
		1082445 DDB1_HUMAN (1-1140): 0: 1424: 100.00		NRBP_HUMAN (2-500): 1.46e-121: 368: 59.36
+	Hs
		320530 DDB1_HUMAN (1-1140): 0: 1424: 100.00		OXSR1_HUMAN (23-501): 1.52e-115: 352: 14.87
+	Hs
		1082440 DDB1_HUMAN (1-1140): 0: 1424: 100.00		KS6B2_HUMAN (17-415): 1.16e-115: 351: 15.63
+	Hs
		1082442 DDB1_HUMAN (1-1140): 0: 1424: 100.00		STK39_HUMAN (34-501): 3.81e-114: 349: 14.78
+	Hs
		1026172 DDB1_HUMAN (1-1140): 0: 1424: 100.00		PAK1_HUMAN (4-317): 4.56e-76: 250: 23.57
+	Dm
		1213442 DDB1_DROME (1-1140): 0: 1237: 60.84		AKT1_DROME (7-374): 6.23e-117: 358: 13.76
+	Hs
		1082408 DDB1_HUMAN (1-1140): 0: 1424: 100.00		PAK6_HUMAN (41-308): 7.79e-09: 60.1: 24.31
+	Dm
		1213429 SF3B3_DROME (3-1126): 0: 1123: 20.68		AKT1_DROME (7-374): 6.23e-117: 358: 13.76
+	Sc
		419973 CFT1_YEAST (11-1125): 0: 678: 14.79		SNF1_YEAST (38-481): 3.66e-100: 316: 15.69
+	Dm
		1213363 Q8T9L6_DROME (517-1126): 0: 610: 19.28		AKT1_DROME (7-374): 6.23e-117: 358: 13.76