HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 26613412, 27571178, 27354282, 35271311, 37689310, 16949367, 20870715, 19287380, 17609381, 17314515, 25557551, 25532805, 25499532, 28202763, 28416635, 30166453, 30590706, 33355139, 35938868, 37024504 and 5 others

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Identification Methods affinity chromatography technology, x-ray crystallography, pull down, proximity labelling technology, unspecified method, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0045732 - positive regulation of protein catabolic process
and 1 others

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Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1140
Hs

1 1507
+ Mm
+ Dm
+ At
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024