HitPredict

Interactor 1: HLF (Q16534)
Hepatic leukemia factor
Gene: HLF

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11983697
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048511 - rhythmic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 295 Hs			1 2442
+	Hs
		547833 ATF2_HUMAN (5-288): 4.28e-34: 131: 18.47		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		579274 ATF4_HUMAN (97-293): 3.34e-31: 120: 16.67		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		402304 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		547790 ATF2_HUMAN (5-288): 4.28e-34: 131: 18.47		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		579259 ATF4_HUMAN (97-293): 3.34e-31: 120: 16.67		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70890 ATF2_MOUSE (5-288): 5.85e-31: 122: 18.47		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Hs
		401902 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70887 JUN_MOUSE (38-290): 5.96e-30: 117: 13.62		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Hs
		569651 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		402629 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		170250 ATF4_HUMAN (97-293): 3.34e-31: 120: 16.67		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		401440 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		402033 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		170248 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		569208 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		401362 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02
+	Hs
		554262 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02
+	Hs
		402260 JUN_HUMAN (10-290): 4.78e-29: 114: 13.16		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		569846 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		569657 CEBPB_HUMAN (189-287): 4.61e-23: 99: 23.23		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09