HitPredict

Interactor 1: MK14 (Q16539)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Gene: MAPK14

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.642

The method score is based on:

Property Details
Experiments 28205554, 20368287
Identification Methods fluorescent resonance energy transfer, two hybrid, affinity chromatography technology, two hybrid pooling approach, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032868 - response to insulin
GO:0046323 - glucose import
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 360
Hs

1 1164
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024