HitPredict

Interactor 1: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Interactor 2: Q86SX1 (Q86SX1)
Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens (human)
Gene: Q86SX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0050821 - protein stabilization GO:0051082 - unfolded protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 262
+	Hs
		1184506 CD37L_HUMAN (45-327): 4.59e-96: 291: 41.05		Q86SX1_HUMAN (1-262): 0: 505: 100.00
+	Hs
		111938 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		K9JA46_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		431897 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Mm
		432430 CDC37_MOUSE (1-377): 2.28e-166: 471: 94.97		HS90A_MOUSE (123-262): 7.34e-84: 266: 99.29
+	Hs
		1082836 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		Q6PK50_HUMAN (141-262): 5.12e-78: 241: 94.26
+	Hs
		438209 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26
+	Hs
		1082801 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		H90B4_HUMAN (152-262): 7.44e-56: 188: 82.88
+	Hs
		1082802 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		H90B3_HUMAN (141-246): 1.13e-53: 184: 87.74
+	Hs
		1082803 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		H90B2_HUMAN (123-256): 2.63e-55: 184: 71.85
+	Hs
		1082805 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		HS904_HUMAN (184-262): 4.63e-40: 144: 91.14
+	Dm
		365455 CDC37_DROME (1-351): 1.28e-126: 371: 52.54		HSP83_DROME (137-262): 3.89e-75: 243: 92.06
+	Ce
		137333 CDC37_CAEEL (2-344): 8.41e-111: 330: 40.00		HSP90_CAEEL (136-262): 9.16e-75: 242: 85.04
+	Hs
		111939 CD37L_HUMAN (45-327): 4.59e-96: 291: 41.05		K9JA46_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		431998 CD37L_HUMAN (45-327): 4.59e-96: 291: 41.05		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		69765 B1AL69_HUMAN (45-302): 1.81e-93: 283: 43.08		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		1162504 CD37L_HUMAN (45-327): 4.59e-96: 291: 41.05		Q6PK50_HUMAN (141-262): 5.12e-78: 241: 94.26
+	Hs
		438303 CD37L_HUMAN (45-327): 4.59e-96: 291: 41.05		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26
+	Sp
		294079 CDC37_SCHPO (2-355): 2.73e-87: 273: 17.35		HSP90_SCHPO (137-262): 2.21e-69: 228: 74.60
+	Sc
		365545 CDC37_YEAST (2-320): 1.81e-73: 238: 18.34		HSP82_YEAST (138-262): 1.99e-70: 231: 75.20
+	Sc
		409878 CDC37_YEAST (2-320): 1.81e-73: 238: 18.34		HSC82_YEAST (138-262): 1.48e-70: 231: 74.40