HitPredict

Interactor 1: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Interactor 2: LMTK3 (Q96Q04)
Serine/threonine-protein kinase LMTK3 (EC 2.7.11.1) (Lemur tyrosine kinase 3)
Gene: LMTK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 378 Hs			1 1460
+	Hs
		789071 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		ABL2_HUMAN (60-983): 5.83e-132: 440: 16.40
+	Hs
		434207 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		RET_HUMAN (4-508): 6.21e-123: 413: 21.40
+	Hs
		601520 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		FGFR2_HUMAN (2-471): 1.02e-125: 413: 21.64
+	Hs
		508026 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		FGFR1_HUMAN (2-458): 1.89e-124: 410: 23.51
+	Hs
		665610 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		EPHB2_HUMAN (6-461): 2.86e-120: 405: 21.46
+	Hs
		665401 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		EPHA3_HUMAN (2-516): 3.34e-119: 400: 20.61
+	Hs
		169179 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		MUSK_HUMAN (13-417): 7.47e-119: 396: 25.65
+	Hs
		609305 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		FGFR3_HUMAN (2-462): 4.72e-119: 394: 24.38
+	Hs
		674444 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		UFO_HUMAN (37-519): 4.72e-107: 364: 24.14
+	Hs
		411738 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		LCK_HUMAN (70-423): 2.76e-111: 363: 24.66
+	Hs
		433785 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		LYN_HUMAN (79-423): 6.29e-109: 357: 23.71
+	Hs
		442838 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		HCK_HUMAN (79-423): 5.93e-109: 357: 24.86
+	Hs
		411399 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		INSR_HUMAN (128-400): 1.19e-40: 166: 36.82
+	Hs
		435654 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		IGF1R_HUMAN (128-400): 3.54e-40: 165: 35.74
+	Hs
		850742 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		BMX_HUMAN (128-404): 1.63e-39: 159: 33.81
+	Hs
		537743 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		INSRR_HUMAN (118-400): 1.71e-37: 156: 36.99
+	Hs
		384911 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		NTRK1_HUMAN (128-417): 1.77e-37: 154: 34.88
+	Hs
		996564 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		ITK_HUMAN (133-408): 2.95e-36: 149: 34.30
+	Hs
		445851 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		ROS1_HUMAN (117-408): 1.38e-33: 144: 33.78
+	Hs
		1018328 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		MERTK_HUMAN (139-416): 2.2e-32: 139: 34.62