Interactor 1: IL17 (Q16552)
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Gene: IL17A

Interactor 2: I17RC (Q8NAC3)
Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14)
Gene: IL17RC

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 17911633, 18684971, 19838198
Identification Methods fluorescence-activated cell sorting, solid phase assay, surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL17~IL17_R_N
Common GO terms GO:0006954 - inflammatory response
GO:0032755 - positive regulation of interleukin-6 production
GO:0038173 - interleukin-17A-mediated signaling pathway
GO:0050832 - defense response to fungus
GO:1900017 - positive regulation of cytokine production involved in inflammatory response
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 155
Hs

1 791
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024