HitPredict

Interactor 1: U1SBP (Q16560)
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)
Gene: SNRNP35

Interactor 2: RNPC3 (Q96LT9)
RNA-binding region-containing protein 3 (RNA-binding motif protein 40) (RNA-binding protein 40) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K)
Gene: RNPC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005689 - U12-type spliceosomal complex
GO:0008380 - RNA splicing
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 246
Hs

1 517
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024