HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 24981860, 33961781, 37689310, 12493763, 35271311, 20388487, 9885572, 21258344
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 425
Hs

1 488
+ Mm
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+ Dm
+ Mm
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+ Dm
+ Dm
+ Ce
+ Hs
+ At
+ At
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+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024