HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: BC11A (Q9H165)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)
Gene: BCL11A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	29263092, 26186194, 28514442, 27705803, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 835
+	Hs
		1083379 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		BC11B_HUMAN (1-835): 0: 596: 57.77
+	Hs
		997899 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		BC11A_HUMAN (1-835): 0: 718: 100.00
+	Hs
		997893 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		BC11B_HUMAN (1-835): 0: 596: 57.77
+	Hs
		1083325 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		ZN296_HUMAN (375-451): 3.26e-11: 68.6: 46.84
+	Hs
		997826 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		ZN296_HUMAN (375-451): 3.26e-11: 68.6: 46.84