HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17803295
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 1045
+	Hs
		997927 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		TOPRS_HUMAN (1-1045): 0: 731: 100.00
+	Ce
		954017 LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16		UNC22_CAEEL (500-955): 3.2e-10: 67: 10.49
+	Hs
		929587 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		DC2I1_HUMAN (552-1024): 8.69e-22: 104: 9.85