HitPredict

Interactor 1: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11

Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23172226
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9, SH3_9~SH3_9
Common GO terms GO:0000165 - MAPK cascade
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004706 - JUN kinase kinase kinase activity
GO:0004709 - MAP kinase kinase kinase activity
and 19 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 847
Hs

1 847
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
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+ Mm
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+ Rn
+ At
+ At
+ Mm
+ Mm
+ At

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Last updated: 15 Jul 2024