HitPredict

Interactor 1: NTRK2 (Q16620)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)
Gene: NTRK2

Interactor 2: PPIP2 (Q9H939)
Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2)
Gene: PSTPIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 334
+	Hs
		1083909 NTRK2_HUMAN (1-822): 0: 638: 100.00		PACN2_HUMAN (7-334): 3.8e-61: 204: 18.57
+	Hs
		608135 FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68		PPIP2_HUMAN (1-334): 5.98e-88: 268: 100.00
+	Hs
		1001578 NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84		FCHO2_HUMAN (1-327): 4.83e-71: 237: 18.26
+	Hs
		607952 FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68		FCHO2_HUMAN (1-327): 4.83e-71: 237: 18.26
+	Hs
		508201 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		PPIP2_HUMAN (1-334): 5.98e-88: 268: 100.00
+	Hs
		1081572 NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84		FNBP1_HUMAN (11-303): 1.92e-64: 216: 18.48
+	Hs
		608003 FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68		FBP1L_HUMAN (11-306): 1.54e-65: 218: 16.07
+	Hs
		1081647 NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84		PACN2_HUMAN (7-334): 3.8e-61: 204: 18.57
+	Hs
		608196 FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68		PACN2_HUMAN (7-334): 3.8e-61: 204: 18.57
+	Hs
		507966 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		FCHO2_HUMAN (1-327): 4.83e-71: 237: 18.26
+	Hs
		253302 NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85		SRGP2_HUMAN (21-334): 1.89e-60: 210: 11.72
+	Hs
		508051 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		FBP1L_HUMAN (11-306): 1.54e-65: 218: 16.07
+	Hs
		508156 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		FNBP1_HUMAN (11-303): 1.92e-64: 216: 18.48
+	Hs
		253307 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		SRGP2_HUMAN (21-334): 1.89e-60: 210: 11.72
+	Hs
		508265 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		PACN2_HUMAN (7-334): 3.8e-61: 204: 18.57
+	Hs
		508089 FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77		NOSTN_HUMAN (13-301): 1.71e-49: 174: 18.43
+	Mm
		555266 FGFR1_MOUSE (129-821): 2.52e-163: 496: 22.67		NOSTN_MOUSE (13-295): 6.53e-16: 80.3: 19.44
+	Hs
		435625 IGF1R_HUMAN (513-797): 1.01e-70: 256: 43.95		FCHO2_HUMAN (1-327): 4.83e-71: 237: 18.26
+	Hs
		253341 ROR2_HUMAN (530-808): 1.44e-69: 249: 44.52		SRGP2_HUMAN (21-334): 1.89e-60: 210: 11.72