HitPredict

Interactor 1: NFE2 (Q16621)
Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2) (Nuclear factor, erythroid-derived 2 45 kDa subunit) (p45 NF-E2)
Gene: NFE2

Interactor 2: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.643

The method score is based on:

Property Details
Experiments 18718448, 11318614
Identification Methods affinity chromatography technology, enzymatic study, two hybrid, far western blotting
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 373
Hs

1 903
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Last updated: 15 Jul 2024