HitPredict

Interactor 1: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 32296183, 10100611, 32512168, 24722188, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~SNARE, SNARE~Syntaxin, Syntaxin~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0001956 - positive regulation of neurotransmitter secretion
GO:0005484 - SNAP receptor activity
GO:0005576 - extracellular region
GO:0005829 - cytosol
and 29 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 288
Hs

1 288
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024