HitPredict

Interactor 1: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Interactor 2: TSNA1 (Q96NA8)
t-SNARE domain-containing protein 1
Gene: TSNARE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SNARE~SNARE, SNARE~Syntaxin
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport GO:0012505 - endomembrane system GO:0031201 - SNARE complex and 1 others more... GO:0048278 - vesicle docking
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 288 Hs			1 513
+	Hs
		47978 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		A0AVG3_HUMAN (1-513): 0: 656: 99.61
+	Hs
		699252 STX1B_HUMAN (1-288): 5.2e-85: 258: 83.33		STX2_HUMAN (249-513): 4.15e-78: 248: 17.78
+	Hs
		699264 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX2_HUMAN (249-513): 4.15e-78: 248: 17.78
+	Mm
		192835 STX1A_MOUSE (1-288): 3.69e-86: 261: 98.26		STX1A_MOUSE (215-512): 6.51e-74: 237: 15.51
+	Hs
		699246 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX2_HUMAN (249-513): 4.15e-78: 248: 17.78
+	Rn
		699169 STX1A_RAT (1-288): 3.03e-86: 261: 98.61		STX1A_RAT (215-512): 9.78e-74: 236: 15.51
+	Hs
		1083928 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX1A_HUMAN (215-512): 6.7e-73: 234: 15.84
+	Hs
		1083946 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX12_HUMAN (247-495): 2.36e-70: 227: 31.33
+	Hs
		898832 STX1B_HUMAN (1-288): 5.2e-85: 258: 83.33		STX4_HUMAN (215-511): 1.12e-67: 221: 15.28
+	Hs
		1017646 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX4_HUMAN (215-511): 1.12e-67: 221: 15.28
+	Hs
		699258 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX4_HUMAN (215-511): 1.12e-67: 221: 15.28
+	Hs
		1030146 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX3_HUMAN (226-512): 1.74e-64: 213: 17.93
+	Hs
		152159 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX16_HUMAN (210-488): 3.83e-64: 213: 18.79
+	Hs
		178555 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX7_HUMAN (259-507): 3.8e-63: 208: 31.33
+	Hs
		152136 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX16_HUMAN (210-488): 3.83e-64: 213: 18.79
+	Hs
		699261 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX3_HUMAN (226-512): 1.74e-64: 213: 17.93
+	Hs
		178411 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX7_HUMAN (259-507): 3.8e-63: 208: 31.33
+	Hs
		1027472 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		STX5_HUMAN (210-491): 4.05e-56: 192: 12.54
+	Hs
		699260 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		STX5_HUMAN (210-491): 4.05e-56: 192: 12.54