HitPredict

Interactor 1: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Interactor 2: HRT3 (Q12347)
F-box protein HRT3 (High level expression reduces Ty3 transposition protein 3)
Gene: HRT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.710

The method score is based on:

Property	Details
Experiments	11805837, 10582239, 14747994, 39437715, 19882662
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, pull down, protein complementation assay
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0030674 - protein-macromolecule adaptor activity and 2 others more... GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0071406 - cellular response to methylmercury
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	815
Sc

1	344

Service provided by Combinatics, Japan

Last updated: 11Aug2025