Interactor 1: OCLN (Q16625)
Occludin
Gene: OCLN

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 14512431, 10026224, 23758859, 10575001, 34079125
Identification Methods pull down, fluorescent resonance energy transfer, affinity chromatography technology, proximity labelling technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0019904 - protein domain specific binding
GO:0035633 - maintenance of blood-brain barrier
GO:0045216 - cell-cell junction organization
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 522
Hs

1 1190
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024