HitPredict

Interactor 1: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 16159877
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 238 Hs			1 904
+	Hs
		952031 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	Hs
		992840 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	At
		1226401 SR30_ARATH (10-89): 1.74e-23: 96.9: 48.78		Q8L7W3_ARATH (1-882): 1.55e-49: 191: 23.98
+	Hs
		257590 NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42		ANR17_HUMAN (107-903): 3.38e-30: 131: 13.10
+	Hs
		1108877 RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05		MA7D1_HUMAN (112-867): 3.1e-27: 121: 9.91
+	Hs
		1259851 PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Hs
		432712 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		MDC1_HUMAN (204-903): 7.29e-13: 75: 9.61
+	Hs
		1084451 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		992772 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		MDC1_HUMAN (204-903): 7.29e-13: 75: 9.61
+	Hs
		1031402 PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Hs
		432998 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		952179 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		516606 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Hs
		132307 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		CAC1A_HUMAN (94-637): 2.17e-09: 63.6: 14.46
+	Hs
		965152 PABP3_HUMAN (6-192): 4.81e-18: 84.4: 14.74		ANK2_HUMAN (110-849): 7.77e-11: 68.6: 14.10
+	Hs
		992995 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		516595 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		KMT2C_HUMAN (390-904): 1.47e-09: 64.6: 11.65
+	Hs
		516749 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		1200910 RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05		Q86V38_HUMAN (108-815): 1.29e-09: 64.2: 10.99
+	Hs
		1200914 RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33		Q86V38_HUMAN (108-815): 1.29e-09: 64.2: 10.99