HitPredict

Interactor 1: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 731
+	Hs
		952047 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		COP1_HUMAN (1-731): 0: 540: 100.00
+	Hs
		1084357 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		1259857 PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		432847 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		992868 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		197006 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		PRP4_HUMAN (511-730): 7.51e-41: 159: 16.59
+	Hs
		952150 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33
+	Hs
		1308786 RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05		NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33
+	Hs
		1314629 RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33		NLE1_HUMAN (582-729): 3.62e-35: 141: 15.33
+	Hs
		903258 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		432626 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		1083259 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34
+	Hs
		903196 PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		903165 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		1084361 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67
+	Hs
		516438 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		952072 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		SNR40_HUMAN (307-447): 5.3e-10: 63.7: 12.67
+	Ce
		953960 Q19581_CAEEL (3-96): 1.46e-16: 80.1: 20.41		LIN53_CAEEL (552-730): 5.7e-14: 76.7: 16.75