HitPredict

Interactor 1: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Interactor 2: SREK1 (Q8WXA9)
Splicing regulatory glutamine/lysine-rich protein 1 (Serine/arginine-rich-splicing regulatory protein 86) (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508) (SRrp508)
Gene: SREK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.831

Property	Details
Experiments	33961781, 14559993
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 508
+	Hs
		432831 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00
+	Hs
		952059 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00
+	Hs
		1031403 PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00		SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00
+	Hs
		992862 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00
+	Hs
		516607 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		SREK1_HUMAN (1-508): 1.81e-52: 187: 100.00
+	At
		790118 PABP2_ARATH (6-88): 7.43e-18: 84: 20.69		CID12_ARATH (20-147): 3.84e-22: 99.4: 29.69
+	Hs
		1084347 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		DC2I1_HUMAN (141-432): 3.42e-10: 64.8: 16.34
+	At
		790115 PABP2_ARATH (6-88): 7.43e-18: 84: 20.69		CID8_ARATH (20-152): 8.54e-16: 80.2: 28.36
+	At
		983454 PABP5_ARATH (9-95): 6.62e-14: 72.4: 24.18		CID8_ARATH (20-152): 8.54e-16: 80.2: 28.36