HitPredict

Interactor 1: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Interactor 2: DDX41 (Q9UJV9)
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)
Gene: DDX41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25920683
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 622
+	Hs
		1263473 SRS12_HUMAN (1-218): 8.5e-28: 108: 32.60		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		432984 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		952172 SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		992985 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		DDX41_HUMAN (1-622): 4.69e-171: 502: 100.00
+	Hs
		1204673 RB15B_HUMAN (4-232): 1.77e-31: 123: 22.41		DDX42_HUMAN (8-620): 5.63e-139: 430: 31.34
+	Hs
		571369 NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42		DDX5_HUMAN (88-617): 1.42e-145: 437: 30.80
+	Hs
		432542 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		DDX5_HUMAN (88-617): 1.42e-145: 437: 30.80
+	Hs
		432838 HNRPC_HUMAN (3-186): 3e-24: 99: 22.58		DDX17_HUMAN (116-622): 2.31e-144: 437: 33.33
+	Hs
		1204678 PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97		DDX42_HUMAN (8-620): 5.63e-139: 430: 31.34
+	Hs
		853939 NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42		DDX42_HUMAN (8-620): 5.63e-139: 430: 31.34
+	Hs
		134018 PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Hs
		133858 PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Mm
		936480 TIAR_MOUSE (5-97): 1.01e-13: 71.3: 23.01		DDX5_MOUSE (88-617): 4.33e-146: 438: 30.80
+	Hs
		1271643 RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33		DDX17_HUMAN (116-622): 2.31e-144: 437: 33.33
+	Hs
		571581 RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33		DDX5_HUMAN (88-617): 1.42e-145: 437: 30.80
+	Dm
		447055 RBP1_DROME (1-80): 1.02e-29: 109: 67.50		VASA1_DROME (169-599): 1.46e-84: 280: 37.76
+	Sc
		376580 PABP_YEAST (7-95): 4.44e-17: 81.7: 22.34		DED1_YEAST (173-589): 1.72e-89: 291: 38.93