HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1584
+	Hs
		1031358 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1056844 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		1084668 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		1056974 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Dm
		631333 BRM_DROME (249-551): 1.19e-45: 175: 20.72		ELYS_DROME (342-1410): 8.95e-19: 95.6: 12.47
+	Hs
		807652 SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Mm
		1150289 SMCA2_MOUSE (137-551): 5.16e-46: 175: 14.44		SRRM2_MOUSE (879-1572): 5.05e-12: 73.7: 12.02
+	Hs
		1031405 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		516609 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		944701 DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59		MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27
+	Hs
		297837 K0754_HUMAN (164-454): 5.35e-16: 84.1: 13.40		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		516749 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		965152 PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Hs
		516595 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		KMT2C_HUMAN (378-1460): 4.45e-12: 73.7: 11.24
+	Hs
		1296684 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Dm
		113976 M9PB30_DROME (190-412): 1.36e-12: 73: 16.67		M9PB30_DROME (122-895): 8.05e-20: 99.4: 8.51
+	Mm
		1351630 PCLO_MOUSE (195-468): 6.01e-14: 77.6: 11.31		PCLO_MOUSE (102-1551): 1.36e-11: 72.2: 7.48
+	Mm
		1111946 SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30		SRRM2_MOUSE (879-1572): 5.05e-12: 73.7: 12.02