HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1133
+	Hs
		1031360 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		516550 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1136287 PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1084626 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1031467 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		516698 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1329984 PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56		RC3H2_HUMAN (1-1107): 0: 1494: 51.72