HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: DHX40 (Q8IX18)
Probable ATP-dependent RNA helicase DHX40 (EC 3.6.4.13) (DEAH box protein 40) (Protein PAD)
Gene: DHX40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 779
+	Hs
		1055381 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		DHX8_HUMAN (45-733): 0: 731: 41.51
+	Hs
		224793 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		DHX16_HUMAN (12-723): 0: 698: 37.68
+	Hs
		1220232 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		994186 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		DHX9_HUMAN (5-773): 0: 622: 22.49
+	Hs
		1220274 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		DHX40_HUMAN (1-779): 0: 782: 100.00
+	Hs
		1055474 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		DHX8_HUMAN (45-733): 0: 731: 41.51
+	Sc
		376861 PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96		PRP43_YEAST (9-732): 0: 695: 36.33
+	Hs
		994314 DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59		DHX9_HUMAN (5-773): 0: 622: 22.49