HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17172643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 551 Hs			1 2442
+	Hs
		846837 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		847041 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		998775 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		846760 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998885 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		846947 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Dm
		115984 BRM_DROME (249-551): 1.19e-45: 175: 20.72		M9PH39_DROME (480-2357): 0: 829: 35.44
+	Hs
		1084666 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		847033 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		846897 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		847093 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		BRWD1_HUMAN (1053-1204): 5.63e-38: 159: 26.83
+	Hs
		631379 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		846778 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		846993 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		BRDT_HUMAN (1059-1195): 1.74e-34: 146: 25.55
+	Hs
		631380 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		846977 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		846812 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Mm
		101535 SMCA2_MOUSE (137-551): 5.16e-46: 175: 14.44		F8VQD1_MOUSE (1040-1275): 7.54e-13: 76.7: 14.41
+	Hs
		847007 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		847103 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68