HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: DAZL (Q92904)
Deleted in azoospermia-like (DAZ homolog) (DAZ-like autosomal) (Deleted in azoospermia-like 1) (SPGY-like-autosomal)
Gene: DAZL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 295
+	Hs
		1235760 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		DAZL_HUMAN (1-295): 1.71e-75: 234: 100.00
+	Hs
		609888 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		ROA2_HUMAN (36-125): 4.39e-24: 101: 18.48
+	Mm
		857339 CPSF6_MOUSE (1-520): 4.58e-92: 294: 99.62		TIA1_MOUSE (35-126): 3.92e-14: 73.7: 23.40
+	Hs
		1031414 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		DAZL_HUMAN (1-295): 1.71e-75: 234: 100.00
+	Hs
		516623 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		DAZL_HUMAN (1-295): 1.71e-75: 234: 100.00
+	Hs
		609957 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		ROA2_HUMAN (36-125): 4.39e-24: 101: 18.48
+	Hs
		609764 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		ROA2_HUMAN (36-125): 4.39e-24: 101: 18.48
+	Hs
		846991 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		RA1L2_HUMAN (30-125): 2.39e-24: 101: 18.37
+	Hs
		516358 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		ROA2_HUMAN (36-125): 4.39e-24: 101: 18.48
+	Hs
		516495 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		PABP1_HUMAN (32-126): 2.67e-16: 81: 18.37
+	Hs
		516339 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		PABP1_HUMAN (32-126): 2.67e-16: 81: 18.37
+	Hs
		668348 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		RBMS1_HUMAN (36-125): 1.7e-09: 59.9: 21.98
+	Zm
		8143 A0A1D6ELH4_MAIZE (60-456): 7.52e-26: 113: 13.55		A0A1D6ELH4_MAIZE (7-126): 2.12e-14: 75.2: 17.89
+	Hs
		516689 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		PABP3_HUMAN (32-126): 2.45e-15: 77.9: 18.37
+	Mm
		665745 PABP1_MOUSE (81-518): 3.65e-24: 108: 16.63		TIA1_MOUSE (35-126): 3.92e-14: 73.7: 23.40
+	Hs
		1104153 TGO1_HUMAN (138-380): 8.27e-13: 73.8: 25.18		RA1L2_HUMAN (30-125): 2.39e-24: 101: 18.37
+	Hs
		516371 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		RBMS1_HUMAN (36-125): 1.7e-09: 59.9: 21.98
+	Dm
		597049 PABP_DROME (81-169): 1.2e-18: 91.5: 24.44		RB27C_DROME (41-182): 1.05e-13: 72.5: 25.16