HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: TRI33 (Q9UPN9)
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)
Gene: TRIM33

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36261009
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1127
+	Hs
		846897 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		TRI33_HUMAN (1-1127): 0: 679: 100.00
+	Hs
		847115 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		TRI33_HUMAN (1-1127): 0: 679: 100.00
+	Hs
		516745 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		TRI33_HUMAN (1-1127): 0: 679: 100.00
+	Hs
		1084554 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		846837 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		847041 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		262171 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		TRIM3_HUMAN (179-629): 2.88e-56: 211: 16.02
+	Hs
		846767 SMCA2_HUMAN (179-551): 2.13e-47: 180: 14.93		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20
+	Hs
		846956 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20
+	Hs
		302284 SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20
+	Hs
		867094 SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20
+	Mm
		1111935 SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30		TIF1B_MOUSE (674-1105): 1.19e-23: 110: 18.62
+	Hs
		1029846 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20
+	Hs
		1030009 ZMIZ1_HUMAN (159-374): 8.13e-09: 60.7: 17.72		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20