HitPredict

Interactor 1: SMN (Q16637)
Survival motor neuron protein (Component of gems 1) (Gemin-1)
Gene: SMN1

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29395067, 10851237
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 95
+	Hs
		1084949 SMN_HUMAN (1-294): 5.52e-150: 423: 100.00		LSM4_HUMAN (1-87): 3.25e-32: 110: 32.58
+	Hs
		912308 SMN_HUMAN (1-294): 5.52e-150: 423: 100.00		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Hs
		912650 SMN_HUMAN (1-294): 5.52e-150: 423: 100.00		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		911854 SMN_HUMAN (1-294): 5.52e-150: 423: 100.00		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		1084861 SMN_HUMAN (1-294): 5.52e-150: 423: 100.00		LSM10_HUMAN (3-87): 2.91e-22: 85: 25.88
+	Dm
		218378 SMN_DROME (27-179): 9.4e-54: 176: 24.68		SMD3_DROME (2-74): 2.73e-23: 88.4: 23.29
+	Hs
		278923 SPF30_HUMAN (44-158): 1.19e-31: 119: 32.17		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43