HitPredict

Interactor 1: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005737 - cytoplasm GO:0005884 - actin filament GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 376
+	Hs
		891799 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		929879 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		ACTG_HUMAN (3-376): 0: 595: 91.44
+	Hs
		932187 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Hs
		915391 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		892099 DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		932439 DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98		ACTC_HUMAN (2-376): 0: 590: 88.27
+	Ce
		501469 Q9XUT0_CAEEL (4-564): 1.01e-44: 171: 16.98		ACT2_CAEEL (1-376): 0: 601: 90.16
+	Hs
		891932 CTTB2_HUMAN (131-644): 3.31e-33: 139: 14.55		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Dm
		950123 TITIN_DROME (173-542): 1.72e-27: 121: 13.80		ACT6_DROME (1-376): 0: 596: 88.83
+	Sc
		551386 ABP1_YEAST (4-508): 1.78e-30: 128: 13.51		ACT_YEAST (1-376): 0: 585: 82.98
+	Dm
		54871 A1ZA72_DROME (119-642): 1.06e-09: 64.1: 10.13		ACT6_DROME (1-376): 0: 596: 88.83
+	Hs
		203220 SYNJ1_HUMAN (103-518): 1.79e-09: 63.3: 9.35		ACTC_HUMAN (2-376): 0: 590: 88.27