HitPredict

Interactor 1: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Interactor 2: OSTF1 (Q92882)
Osteoclast-stimulating factor 1
Gene: OSTF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 721 Hs			1 214
+	Hs
		1021411 MK06_HUMAN (1-721): 0: 638: 100.00		ANK3_HUMAN (7-213): 1.88e-34: 131: 14.46
+	Hs
		1085500 MK06_HUMAN (1-721): 0: 638: 100.00		ANKR2_HUMAN (80-213): 6.96e-32: 120: 23.13
+	Hs
		1085426 MK06_HUMAN (1-721): 0: 638: 100.00		ANKH1_HUMAN (3-128): 7.84e-15: 74.6: 18.90
+	Hs
		658865 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		DAPK1_HUMAN (3-192): 1.86e-34: 131: 24.08
+	Hs
		647524 MK03_HUMAN (8-360): 7.75e-133: 399: 41.41		DAPK1_HUMAN (3-192): 1.86e-34: 131: 24.08
+	Hs
		625621 CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19		RAI14_HUMAN (3-209): 5.5e-34: 130: 19.23
+	Hs
		659031 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		BARD1_HUMAN (136-213): 9.08e-17: 80: 20.51
+	Rn
		926505 MK01_RAT (8-354): 3.79e-137: 409: 41.83		TANC1_RAT (122-213): 2.23e-15: 76.1: 17.90
+	Hs
		166888 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		ANR28_HUMAN (3-161): 7.49e-14: 71.5: 18.79
+	Hs
		625577 CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19		BARD1_HUMAN (136-213): 9.08e-17: 80: 20.51
+	Mm
		926405 MK01_MOUSE (8-354): 3.79e-137: 409: 41.83		TNKS2_MOUSE (2-126): 1.16e-10: 62.3: 18.25
+	Hs
		659047 MK01_HUMAN (8-354): 5.92e-137: 408: 41.83		TNKS2_HUMAN (2-126): 9.21e-11: 62.7: 18.25