Interactor 1: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.860

The method score is based on:

Property Details
Experiments 27320910, 20562859, 16126907, 12050673
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAS~PAS, PAS~PAS_3, PAS_3~PAS_3
Common GO terms GO:0000302 - response to reactive oxygen species
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
and 113 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 826
Hs

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Last updated: 15 Jul 2024