Interactor 1: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 17502379
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 826
Hs

1 1335
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024