Interactor 1: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Interactor 2: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 25665578, 31665637, 24237704, 9718316
Identification Methods affinity chromatography technology, cross-linking study, pull down
Interaction Type physical association, self interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HIN~HIN, PYRIN~PYRIN
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001819 - positive regulation of cytokine production
GO:0002218 - activation of innate immune response
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
and 30 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 785
Hs

1 785
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024