HitPredict

Interactor 1: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Interactor 2: EXOS6 (Q5RKV6)
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
Gene: EXOSC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25693804, 25665578, 31665637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 272
+	Hs
		1085969 IF16_HUMAN (1-785): 0: 1155: 100.00		EXOS4_HUMAN (20-267): 1.16e-77: 237: 26.51
+	Hs
		1085874 IF16_HUMAN (1-785): 0: 1155: 100.00		EXOS8_HUMAN (16-265): 1.31e-63: 202: 16.19
+	Hs
		1063721 IF16_HUMAN (1-785): 0: 1155: 100.00		EXOS7_HUMAN (11-271): 3.95e-56: 183: 17.07
+	Hs
		1153938 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		EXOS4_HUMAN (20-267): 1.16e-77: 237: 26.51
+	Hs
		781755 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		EXOS6_HUMAN (1-272): 6.04e-63: 200: 100.00
+	Hs
		781747 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		EXOS7_HUMAN (11-271): 3.95e-56: 183: 17.07
+	Hs
		986684 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		EXOS9_HUMAN (9-271): 3.87e-49: 169: 13.22