HitPredict

Interactor 1: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Interactor 2: WDR75 (Q8IWA0)
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)
Gene: WDR75

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25693804, 25665578
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 830
+	Hs
		1016285 IF16_HUMAN (1-785): 0: 1155: 100.00		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Hs
		1086040 IF16_HUMAN (1-785): 0: 1155: 100.00		WDR3_HUMAN (510-738): 3.01e-19: 95.4: 15.95
+	Hs
		1085988 IF16_HUMAN (1-785): 0: 1155: 100.00		NLE1_HUMAN (530-700): 1.91e-18: 91.2: 8.94
+	Hs
		863450 IF16_HUMAN (1-785): 0: 1155: 100.00		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59
+	Hs
		1085854 IF16_HUMAN (1-785): 0: 1155: 100.00		PHIP_HUMAN (19-142): 2.17e-14: 79.8: 15.75
+	Hs
		781769 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		WDR75_HUMAN (1-830): 2.39e-177: 533: 95.36
+	Hs
		781730 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Hs
		1016290 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Hs
		781854 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		WDR3_HUMAN (510-738): 3.01e-19: 95.4: 15.95
+	Hs
		781720 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59
+	Hs
		863461 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59
+	Hs
		1153882 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		PHIP_HUMAN (19-142): 2.17e-14: 79.8: 15.75
+	Hs
		867876 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		HIRA_HUMAN (493-636): 8.61e-11: 67.9: 10.00
+	Hs
		157023 AIM2_HUMAN (496-765): 5.95e-89: 285: 37.68		COPA_HUMAN (5-364): 2.65e-16: 86: 12.59
+	Hs
		157024 AIM2_HUMAN (496-765): 5.95e-89: 285: 37.68		HIRA_HUMAN (493-636): 8.61e-11: 67.9: 10.00