HitPredict

Interactor 1: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Interactor 2: DHX58 (Q96C10)
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)
Gene: DHX58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045824 - negative regulation of innate immune response
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 678
+	Hs
		229414 IF16_HUMAN (1-785): 0: 1155: 100.00		SMCA5_HUMAN (2-611): 7.74e-78: 270: 12.38
+	Hs
		1059645 IF16_HUMAN (1-785): 0: 1155: 100.00		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		658683 IF16_HUMAN (1-785): 0: 1155: 100.00		SMCA1_HUMAN (3-611): 3.05e-74: 260: 12.31
+	Hs
		1085939 IF16_HUMAN (1-785): 0: 1155: 100.00		DDX24_HUMAN (3-557): 6.6e-57: 209: 14.35
+	Hs
		134064 IF16_HUMAN (1-785): 0: 1155: 100.00		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		571477 IF16_HUMAN (1-785): 0: 1155: 100.00		DDX5_HUMAN (2-255): 1.99e-37: 150: 15.21
+	Hs
		1085881 IF16_HUMAN (1-785): 0: 1155: 100.00		DDX27_HUMAN (2-371): 4.82e-10: 64.9: 16.27
+	Hs
		1153976 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		DICER_HUMAN (3-515): 7.66e-90: 309: 21.54
+	Hs
		229424 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		SMCA5_HUMAN (2-611): 7.74e-78: 270: 12.38
+	Hs
		1059675 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		658692 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		SMCA1_HUMAN (3-611): 3.05e-74: 260: 12.31
+	Hs
		156988 AIM2_HUMAN (496-765): 5.95e-89: 285: 37.68		SMCA5_HUMAN (2-611): 7.74e-78: 270: 12.38
+	Hs
		157043 AIM2_HUMAN (496-765): 5.95e-89: 285: 37.68		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		781816 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		DDX24_HUMAN (3-557): 6.6e-57: 209: 14.35
+	Hs
		781791 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		DDX27_HUMAN (2-371): 4.82e-10: 64.9: 16.27