HitPredict

Interactor 1: G5EGR6 (G5EGR6)
Protein argonaute-2
Gene: alg-1

Interactor 2: LIN41 (Q9U489)
Protein lin-41 (Abnormal cell lineage protein 41)
Gene: lin-41

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23599497, 26351692
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005737 - cytoplasm GO:0035198 - miRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1002 Ce			1 1147
+	Hs
		1102507 AGO2_HUMAN (132-1002): 0: 1142: 67.09		LIN41_HUMAN (349-1147): 1.44e-127: 413: 32.30
+	Mm
		1093411 AGO2_MOUSE (114-1002): 0: 1142: 66.29		LIN41_MOUSE (365-1147): 3.79e-125: 406: 31.94
+	Hs
		585070 AGO3_HUMAN (127-1002): 0: 1129: 65.09		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		585074 AGO4_HUMAN (121-1002): 0: 1102: 64.02		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		1282069 AGO2_HUMAN (132-1002): 0: 1142: 67.09		TRI63_HUMAN (361-673): 7.46e-59: 208: 15.18
+	Hs
		1317538 AGO2_HUMAN (132-1002): 0: 1142: 67.09		TRI55_HUMAN (366-673): 6.7e-49: 185: 12.99
+	Dm
		1103832 Q32KD4_DROME (37-1002): 0: 1171: 63.05		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Dm
		1103862 Q32KD4_DROME (37-1002): 0: 1171: 63.05		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Ce
		247863 ERGO1_CAEEL (443-960): 4.86e-49: 191: 27.33		LIN41_CAEEL (1-1147): 0: 1087: 100.00
+	Mm
		1208468 AGO1_MOUSE (126-1002): 0: 1139: 65.95		TRI32_MOUSE (878-1147): 2.31e-29: 127: 23.26
+	Dm
		1103819 Q32KD4_DROME (37-1002): 0: 1171: 63.05		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Ce
		1094449 WAGO1_CAEEL (334-957): 1.74e-36: 151: 24.69		LIN41_CAEEL (1-1147): 0: 1087: 100.00
+	Hs
		170508 AGO2_HUMAN (132-1002): 0: 1142: 67.09		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Hs
		170510 AGO1_HUMAN (126-1002): 0: 1139: 65.95		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100038 Q27IR0_DROME (113-956): 0: 1074: 68.37		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Hs
		170478 AGO3_HUMAN (127-1002): 0: 1129: 65.09		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100039 Q27IR0_DROME (113-956): 0: 1074: 68.37		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Hs
		170484 AGO4_HUMAN (121-1002): 0: 1102: 64.02		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100037 Q27IR0_DROME (113-956): 0: 1074: 68.37		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Hs
		1294945 PIWL1_HUMAN (57-964): 0: 762: 20.65		TRI54_HUMAN (366-704): 2.45e-58: 207: 13.54