HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	27934968, 11163245
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HAT_KAT11~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 2442
+	Hs
		935066 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		934698 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998779 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		952296 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		935038 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		935372 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		170326 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		170333 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		631395 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		934782 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631400 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		934930 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Mm
		101827 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		F8WI37_MOUSE (1733-2440): 7.05e-13: 77.1: 11.27
+	Hs
		1086201 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		934702 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		1017307 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		935324 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Mm
		93660 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		E9Q6A7_MOUSE (1831-2279): 8.68e-12: 73.6: 11.04
+	Hs
		935004 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		1086228 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89