HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12700765
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1210
+	Hs
		935126 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		952553 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1174632 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Mm
		952777 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		EHMT2_MOUSE (9-1210): 0: 870: 94.44
+	Hs
		935251 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1086320 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		952633 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Dm
		115784 H3_DROME (1-136): 1.34e-60: 184: 96.32		M9PGH7_DROME (1-1210): 5.56e-155: 507: 23.23
+	Hs
		934668 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		ANK2_HUMAN (441-952): 4.59e-91: 326: 18.61
+	Hs
		965127 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		ANK2_HUMAN (441-952): 4.59e-91: 326: 18.61
+	At
		886462 H33_ARATH (1-136): 1.13e-61: 187: 93.38		SUVH4_ARATH (911-1177): 1.21e-82: 285: 29.13
+	Hs
		935237 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		SUV92_HUMAN (928-1177): 2.53e-85: 285: 35.93
+	Hs
		952627 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		SUV92_HUMAN (928-1177): 2.53e-85: 285: 35.93
+	Hs
		203659 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		203664 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		203722 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		934710 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		ANK3_HUMAN (624-1084): 7.02e-66: 248: 17.79
+	Sp
		223811 H31_SCHPO (1-136): 4.67e-59: 180: 88.97		CLR4_SCHPO (924-1176): 3.8e-36: 145: 34.95
+	Dm
		356073 H3_DROME (1-136): 1.34e-60: 184: 96.32		SUV39_DROME (934-1176): 1.28e-28: 125: 36.84
+	At
		886666 H31_ARATH (1-136): 3.02e-60: 183: 94.12		SUVR2_ARATH (925-1176): 6.59e-29: 126: 30.97