HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: VRK1 (Q99986)
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
Gene: VRK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	26068304, 29340707
Identification Methods	affinity chromatography technology, protein kinase assay
Interaction Type	physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 396
+	At
		886659 H31_ARATH (1-136): 3.02e-60: 183: 94.12		CDPK4_ARATH (15-386): 5.81e-106: 322: 13.85
+	At
		886660 H31_ARATH (1-136): 3.02e-60: 183: 94.12		CDPKB_ARATH (15-386): 8.54e-106: 322: 13.85
+	Sc
		419937 H3_YEAST (1-136): 1.43e-55: 171: 86.03		SNF1_YEAST (19-370): 8.56e-105: 324: 13.80
+	Hs
		935173 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		952585 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		1174643 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Sc
		419855 CENPA_YEAST (18-134): 1.65e-41: 139: 53.33		SNF1_YEAST (19-370): 8.56e-105: 324: 13.80
+	Hs
		828359 CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		952454 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		VRK3_HUMAN (21-329): 4.13e-62: 208: 36.08