HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21081666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1122
+	Hs
		935381 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		952704 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Mm
		952741 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		Q3UJF1_MOUSE (1-1122): 0: 717: 92.71
+	Hs
		952692 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		HDAC9_HUMAN (25-1055): 0: 608: 56.33
+	Hs
		1174685 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		HDAC9_HUMAN (25-1055): 0: 608: 56.33
+	Hs
		934735 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		935063 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		1038423 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		1086250 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		952319 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		952512 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		111560 K7EK07_HUMAN (1-132): 3.48e-59: 180: 93.18		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		177255 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Mm
		952773 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		Q9JM08_MOUSE (679-1119): 5.71e-142: 436: 21.57
+	Sc
		693050 H3_YEAST (1-136): 1.43e-55: 171: 86.03		RPD3_YEAST (665-1098): 4.72e-146: 446: 22.00
+	Sc
		866875 H3_YEAST (1-136): 1.43e-55: 171: 86.03		HDA1_YEAST (658-1097): 4.56e-140: 441: 32.32
+	Hs
		828220 CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Ce
		184839 HCP3_CAEEL (11-131): 7.65e-45: 149: 46.77		HDA1_CAEEL (669-1121): 6.71e-140: 431: 20.46
+	Hs
		935331 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97
+	Sc
		859059 H3_YEAST (1-136): 1.43e-55: 171: 86.03		HOS2_YEAST (704-1005): 7.92e-24: 108: 28.39