Interactor 1: CLPP (Q16740)
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)
Gene: CLPP

Interactor 2: CLPP (Q16740)
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)
Gene: CLPP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 31056398, 20637416, 15522782
Identification Methods proximity labelling technology, cosedimentation in solution, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CLP_protease~CLP_protease
Common GO terms GO:0004175 - endopeptidase activity
GO:0004176 - ATP-dependent peptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
and 8 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 277
Hs

1 277
+ Ec
+ Ss
+ Hp
+ Bs
+ At
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024