HitPredict

Interactor 1: UBE2S (Q16763)
Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)
Gene: UBE2S

Interactor 2: UBE2S (Q16763)
Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)
Gene: UBE2S

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25306923, 27685940, 30903204, 31230944, 33082289, 34942047, 20622874, 8576261, 20061386
Identification Methods enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, unspecified method
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~UQ_con
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 17 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 222
Hs

1 222
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Last updated: 15 Jul 2024