HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	24518117, 19203578, 21041483, 22492721, 22980979
Identification Methods	enzymatic study, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 129 Hs			1 571
+	Hs
		1151353 H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		1185204 H2A3_HUMAN (1-127): 5.35e-65: 195: 95.28		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		470451 H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		391788 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		555539 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		555503 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		NIPBL_HUMAN (87-561): 1.57e-63: 228: 13.92
+	Hs
		1087056 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		1151358 H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		391801 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		RN169_HUMAN (13-432): 1.06e-29: 126: 23.85
+	Hs
		1264786 H2A1H_HUMAN (1-127): 1.77e-65: 196: 96.06		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05
+	Hs
		470480 H2A1_HUMAN (1-127): 5.35e-65: 195: 96.06		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05
+	Hs
		391817 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05