HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	8684459, 16096645
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 129 Hs			1 837
+	Hs
		391824 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		KAT2A_HUMAN (75-837): 0: 1159: 100.00
+	Mm
		1151749 H2A2A_MOUSE (1-127): 3.37e-65: 195: 97.64		KAT2B_MOUSE (31-837): 0: 1136: 71.46
+	Hs
		1087073 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		KAT2B_HUMAN (84-837): 0: 1095: 74.31
+	Hs
		391825 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		KAT2B_HUMAN (84-837): 0: 1095: 74.31
+	Hs
		998781 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		998866 H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		391671 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		631492 H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Mm
		70932 H2A3_MOUSE (1-127): 5.35e-65: 195: 95.28		EP300_MOUSE (652-832): 1.14e-36: 151: 17.94
+	Hs
		391554 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		555299 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		1066979 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		1067038 H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		1067005 H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		244634 H2A2B_HUMAN (1-126): 2.4e-66: 198: 96.83		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		244795 H2A1H_HUMAN (1-127): 1.77e-65: 196: 96.06		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		244848 H2A1J_HUMAN (1-127): 9.26e-66: 196: 96.06		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		243783 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		1087066 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70
+	Hs
		391923 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		BAZ1A_HUMAN (735-834): 1e-11: 71.2: 30.00