HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: UBP16 (Q9Y5T5)
Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16)
Gene: USP16

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	21245042, 17914355
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 129 Hs			1 823
+	Hs
		1151401 H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64		UBP16_HUMAN (1-823): 0: 628: 100.00
+	Hs
		391987 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		UBP16_HUMAN (1-823): 0: 628: 100.00
+	Hs
		1087139 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		UBP20_HUMAN (17-821): 3.01e-112: 365: 18.72
+	Hs
		1087027 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		UBP51_HUMAN (465-821): 3.12e-48: 184: 20.38
+	Hs
		1087135 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		UBP22_HUMAN (454-823): 6.46e-48: 180: 19.42
+	Hs
		391756 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		UBP51_HUMAN (465-821): 3.12e-48: 184: 20.38
+	Hs
		391971 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		UBP22_HUMAN (454-823): 6.46e-48: 180: 19.42
+	Hs
		271104 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		UBP2_HUMAN (629-820): 1.25e-39: 157: 26.94
+	Hs
		271018 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		UBP2_HUMAN (629-820): 1.25e-39: 157: 26.94
+	Hs
		391991 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		UBP3_HUMAN (527-819): 1.63e-37: 149: 22.19
+	Hs
		555516 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		UBP49_HUMAN (611-821): 5.62e-16: 84.3: 30.84
+	Hs
		1087144 H2A2C_HUMAN (1-129): 7.11e-67: 199: 100.00		UBP15_HUMAN (388-558): 4.48e-10: 65.5: 7.47
+	Hs
		555362 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		UBP11_HUMAN (393-556): 2.64e-11: 69.4: 8.82
+	Sc
		392501 H2A2_YEAST (16-129): 1.63e-52: 163: 78.95		UBP8_YEAST (629-819): 7.6e-18: 89.4: 33.16